JAMA Psychiatry:非典型重度抑郁症是肥胖有力预测因素

2014-06-13 CMT 医学论坛网

一项瑞士研究表明,非典型重度抑郁症(MDD)是肥胖的有力预测因素,建议采取治疗措施应对疾病发作期间食欲增加所致的不良后果。文章6月4日在线发表于《美国医学会杂志·精神病学》(JAMA Psychiatry)。 研究纳入3054例受试者并随访5.5年。结果显示,仅基线时非典型MDD患者表现出较非MDD受试者显著升高的肥胖发病率。校正大量可能的混杂因素后,非典型MDD与体质指数、肥胖发病率、腰围

一项瑞士研究表明,非典型重度抑郁症(MDD)是肥胖的有力预测因素,建议采取治疗措施应对疾病发作期间食欲增加所致的不良后果。文章6月4日在线发表于《美国医学会杂志·精神病学》(JAMA Psychiatry)。

研究纳入3054例受试者并随访5.5年。结果显示,仅基线时非典型MDD患者表现出较非MDD受试者显著升高的肥胖发病率。校正大量可能的混杂因素后,非典型MDD与体质指数、肥胖发病率、腰围及男性脂肪量仍显著相关。



原始出处:

Lasserre AM1, Glaus J2, Vandeleur CL1, Marques-Vidal P3, Vaucher J4, Bastardot F4, Waeber G4, Vollenweider P4, Preisig M1.Depression With Atypical Features and Increase in Obesity, Body Mass Index, Waist Circumference, and Fat Mass: A Prospective, Population-Based Study.JAMA Psychiatry. 2014 Jun 4. doi: 10.1001/jamapsychiatry.2014.411.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1791869, encodeId=e3ef1e91869e3, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Sun Jan 25 04:45:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20789, encodeId=0d1b20e895f, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20790, encodeId=e68a20e902e, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264211, encodeId=2058126421103, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492579, encodeId=c20f14925e901, content=<a href='/topic/show?id=9b7c9929363' target=_blank style='color:#2F92EE;'>#非典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99293, encryptionId=9b7c9929363, topicName=非典型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb98946820, createdName=sjzlzc010, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1791869, encodeId=e3ef1e91869e3, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Sun Jan 25 04:45:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20789, encodeId=0d1b20e895f, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20790, encodeId=e68a20e902e, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264211, encodeId=2058126421103, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492579, encodeId=c20f14925e901, content=<a href='/topic/show?id=9b7c9929363' target=_blank style='color:#2F92EE;'>#非典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99293, encryptionId=9b7c9929363, topicName=非典型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb98946820, createdName=sjzlzc010, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=)]
    2015-04-11 x35042875

    国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1791869, encodeId=e3ef1e91869e3, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Sun Jan 25 04:45:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20789, encodeId=0d1b20e895f, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20790, encodeId=e68a20e902e, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264211, encodeId=2058126421103, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492579, encodeId=c20f14925e901, content=<a href='/topic/show?id=9b7c9929363' target=_blank style='color:#2F92EE;'>#非典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99293, encryptionId=9b7c9929363, topicName=非典型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb98946820, createdName=sjzlzc010, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=)]
    2015-04-11 x35042875

    国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1791869, encodeId=e3ef1e91869e3, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Sun Jan 25 04:45:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20789, encodeId=0d1b20e895f, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20790, encodeId=e68a20e902e, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264211, encodeId=2058126421103, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492579, encodeId=c20f14925e901, content=<a href='/topic/show?id=9b7c9929363' target=_blank style='color:#2F92EE;'>#非典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99293, encryptionId=9b7c9929363, topicName=非典型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb98946820, createdName=sjzlzc010, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1791869, encodeId=e3ef1e91869e3, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Sun Jan 25 04:45:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20789, encodeId=0d1b20e895f, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20790, encodeId=e68a20e902e, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:45:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264211, encodeId=2058126421103, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492579, encodeId=c20f14925e901, content=<a href='/topic/show?id=9b7c9929363' target=_blank style='color:#2F92EE;'>#非典型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99293, encryptionId=9b7c9929363, topicName=非典型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb98946820, createdName=sjzlzc010, createdTime=Sun Jun 15 07:45:00 CST 2014, time=2014-06-15, status=1, ipAttribution=)]

相关资讯

Spine J:抑郁症是腰椎管狭窄手术预后的预测因素

疼痛和活动受限是腰椎管狭窄(LSS)常见临床症状,可作为判断患者腰椎状况的依据。既往有研究表明,通过 SF-36简明评分可发现腰部术后的患者如果罹患抑郁症则会导致术后功能恢复减慢;很多综述类的文献也证明抑郁症是腰痛独立的预测因素;包括抑郁症在内的心理因素可影响LSS的疼痛等临床症状及其他相关问题的预后。 最近有研究发现LSS患者生存质量下降,与同龄的慢性腰痛的患者相比并发症的发生率增加,这说

JAMA子刊:听力障碍的成年人易患抑郁症

据路透社报道,在一项涉及全美的调查中发现,患有听力障碍的成年人,比那些拥有出色听觉的人更容易患上抑郁症。并且,抑郁症在中年妇女当中发生率更高。 研究人员分析了从2005年至2010年的调查数据,超过18000名18岁以上的成年人,在问卷中回答了关于他们的精神和身体健康的问题。 在听力评估的问卷选项里,近80%的受访者表示,具有良好或优秀的听力,其中,年龄在70岁以上的人,需经过医生审查。 而

Science:科学家“以毒攻毒”治抑郁症

通常人们治病都是找出根源后设法消灭它,但美国一项治疗抑郁症的新研究则反其道而行,通过加强抑郁症的致病机制来达到治疗效果。这种类似“以毒攻毒”的策略开辟了治疗抑郁症的一条全新途径。 该项研究负责人、纽约伊坎医学院助理教授韩明虎对新华社记者说,他们研究发现,大脑受到不良刺激后未患抑郁症的小鼠,其大脑并不像之前认为的那样努力避免有害变化,而是经历了有害变化,并利用它们建立了新的健康平衡。该研究17

Molecular Brain:深部脑磁刺激可能促进海马神经再生和缓解应激压力

海马是大脑中的一个重要区域,在学习记忆、情绪情感等脑功能活动中发挥重要作用。正常动物成年海马的齿状回不断有新的神经细胞出现,这种现象叫做神经干细胞增殖或是神经发生。压力或衰老会阻断海马中的这种神经细胞新生,这可能是抑郁症的病因所在。【原文下载】 恢复海马神经细胞新生的能力是抑郁症得以康复的必由之路。2000年诺贝尔奖获得者Erickandel在他的自传In search of memory(

JAMA:社区特点对精神健康的影响或存性别差异

据3月5日刊《美国医学会杂志》上的一则研究披露,对那些搬离高度贫困社区的家庭而言,这些家庭中的男孩经历了抑郁症及行为障碍比率的增加而女孩在这些方面则有下降。 观察性研究总是发现,在高度贫困社区中的青少年有着情绪问题的高发病这些发现提出了社区特点会影响情绪功能,而社区层面的干预可能会减少情绪问题的可能性。根据文章的背景资料,来自可获得的观察性研究的数据是不清楚的。“了解社区对精神健康的影响对构

Diabetes Care:炎症可能是糖尿病与抑郁症相关联的纽带

既往研究显示,糖尿病患者抑郁症的发生率较高,合并抑郁症的糖尿病患者的长期健康结局更差。一项最新研究表明,与单纯糖尿病患者相比,合并抑郁症的糖尿病患者血液中炎症标志物的水平更高,炎症可能是联系糖尿病与抑郁症的纽带。 研究者英国伦敦国王学院的Khalida Ismail及其同事对1227例新诊断的2型糖尿病患者的分析发现,与单纯糖尿病患者相比,合并抑郁症的糖尿病患者更年轻、体重更重、心血管疾病发病率