GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase

Liang, RJ; Taylor, S; Nahiyaan, N; Song, J; Murphy, CJ; Dantas, E; Cheng, SY; Hsu, TW; Ramsamooj, S; Grover, R; Hwang, SK; Ngo, B; Cantley, LC; Rhee, KY; Goncalves, MD

Goncalves, MD (corresponding author), Weill Cornell Med, Div Endocrinol, Weill Dept Med, New York, NY 10065 USA.; Goncalves, MD (corresponding author), Weill Cornell Med, Dept Med, Meyer Canc Ctr, New York, NY 10065 USA.

CANCER & METABOLISM, 2021; 9 (1):

Abstract

Background Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferat......

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