Antibody-drug conjugates of 7-ethyl-10-hydroxycamptothecin: Sacituzumab govitecan and labetuzumab govitecan

Dong, WJ; Shi, JY; Yuan, T; Qi, BW; Yu, JY; Dai, JY; He, L

Dai, JY; He, L (reprint author), Univ Elect Sci & Technol China, Sch Med, Sichuan Acad Med Sci, Chengdu 610072, Sichuan, Peoples R China.; Dai, JY; He, L (reprint author), Univ Elect Sci & Technol China, Sch Med, Sichuan Prov Peoples Hosp, Chengdu 610072,

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019; 167 (): 583

Abstract

Monoclonal antibody (mAb), cytotoxins, and linker technology are three essential elements for developing a successful antibody-drug conjugate (ADC). I......

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