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Porcine Decellularized Diaphragm Hydrogel: A New Option for Skeletal Muscle Malformations

期刊: BIOMEDICINES, 2021; 9 (7)

Hydrogels are biomaterials that, thanks to their unique hydrophilic and biomimetic characteristics, are used to support cell growth and attachment and......

miR-31-5p Promotes Oxidative Stress and Vascular Smooth Muscle Cell Migration in Spontaneously Hypertensive Rats via Inhibiting FNDC5 Expression

期刊: BIOMEDICINES, 2021; 9 (8)

Oxidative stress and the migration of vascular smooth muscle cells (VSMCs) are important for vascular remodeling in a variety of vascular diseases. mi......

Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice

期刊: BIOMEDICINES, 2021; 9 (8)

Acetaminophen (APA)-induced hepatotoxicity is coupled with the activation of autophagy. We sought to determine whether selective autophagy of the endo......

Longitudinal Circulating Levels of miR-23b-3p, miR-126-3p and lncRNA GAS5 in HCC Patients Treated with Sorafenib

期刊: BIOMEDICINES, 2021; 9 (7)

Human hepatocellular carcinoma (HCC) is the most frequent primary tumor of the liver and the third cause of cancer-related deaths. The multikinase inh......

Aging Additively Influences Insulin- and Insulin-Like Growth Factor-1-Mediated Endothelial Dysfunction and Antioxidant Deficiency in Spontaneously Hypertensive Rats

期刊: BIOMEDICINES, 2021; 9 (6)

This study aimed to investigate the aging-related endothelial dysfunction mediated by insulin and insulin-like growth factor-1 (IGF-1) and antioxidant......

Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation

期刊: BIOMEDICINES, 2021; 9 (4)

Tendon defects require multimodal therapeutic management over extensive periods and incur high collateral burden with frequent functional losses. Spec......

Anti-Toxoplasma gondii Effects of a Novel Spider Peptide XYP1 In Vitro and In Vivo

期刊: BIOMEDICINES, 2021; 9 (8)

Toxoplasmosis, caused by an obligate intracellular parasite Toxoplasma gondii, is one of the most prevalent zoonoses worldwide. Treatments for this di......

beta-Elemene Suppresses Obesity-Induced Imbalance in the Microbiota-Gut-Brain Axis

期刊: BIOMEDICINES, 2021; 9 (7)

As a kind of metabolically triggered inflammation, obesity influences the interplay between the central nervous system and the enteral environment. Th......

Genetic Diversity of SARS-CoV-2 over a One-Year Period of the COVID-19 Pandemic: A Global Perspective

期刊: BIOMEDICINES, 2021; 9 (4)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic of coronavirus disease in 2019 (COVID-19). Genome surveillance i......

Gene Module Analysis Reveals Cell-Type Specificity and Potential Target Genes in Autism's Pathogenesis

期刊: BIOMEDICINES, 2021; 9 (4)

Multiple genetic factors contribute to the pathogenesis of autism spectrum disorder (ASD), a kind of neurodevelopmental disorder. Genes were usually s......

Combination of Mesenchymal Stem Cell-Delivered Oncolytic Virus with Prodrug Activation Increases Efficacy and Safety of Colorectal Cancer Therapy

期刊: BIOMEDICINES, 2021; 9 (5)

Although oncolytic viruses are currently being evaluated for cancer treatment in clinical trials, systemic administration is hindered by many factors ......

Long COVID-19 Syndrome: A Comprehensive Review of Its Effect on Various Organ Systems and Recommendation on Rehabilitation Plans

期刊: BIOMEDICINES, 2021; 9 (8)

The majority of people infected with SARS-CoV-2 fully recovered within a few weeks. However, a considerable number of patients of different ages still......

Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice

期刊: BIOMEDICINES, 2021; 9 (5)

Fatty acid-binding proteins (FABPs) regulate the intracellular dynamics of fatty acids, mediate lipid metabolism and participate in signaling processe......

Histone H2B Mutations in Cancer

期刊: BIOMEDICINES, 2021; 9 (6)

Oncohistones have emerged as a new area in cancer epigenetics research. Recent efforts to catalogue histone mutations in cancer patients have revealed......

3D-Printed Ginsenoside Rb1-Loaded Mesoporous Calcium Silicate/Calcium Sulfate Scaffolds for Inflammation Inhibition and Bone Regeneration

期刊: BIOMEDICINES, 2021; 9 (8)

Bone defects are commonly found in the elderly and athletic population due to systemic diseases such as osteoporosis and trauma. Bone scaffolds have s......

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