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1987 2
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Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors.
Vorce RL, Goodman JI. Vorce RL, et al. Mol Toxicol. 1989 Apr-Jun;2(2):99-116. Mol Toxicol. 1989. PMID: 2702305
These results support the assertion that tumors induced by different classes of carcinogens or arising spontaneously share common biochemical pathways of oncogene activation during tumorigenesis....
These results support the assertion that tumors induced by different classes of carcinogens or arising spontaneously share common biochem …
Validation project of alternatives for the Draize eye test.
Kalweit S, Gerner I, Spielmann H. Kalweit S, et al. Mol Toxicol. 1987-1988 Fall;1(4):597-603. Mol Toxicol. 1987. PMID: 3509706
Under the current research scheme, which is coordinated by the West German Public Health Office (BGA), 14 toxicology laboratories in the chemical industry, universities, the BGA, and other research institutions are to study 44 substances with a variety of chemical, biochemical …
Under the current research scheme, which is coordinated by the West German Public Health Office (BGA), 14 toxicology laboratories in the che …
Biotransformation enzymes in two renal epithelial cell lines (LLC-PK1 and RK-L).
Siegers CP, Denker S, Steffen B, Jelkmann W. Siegers CP, et al. Mol Toxicol. 1987-1988 Fall;1(4):335-9. Mol Toxicol. 1987. PMID: 3509689
The glutathione content in both epithelial cell lines can be modified by an inhibitor of GSH synthesis (buthionine sulfoximine, BSO), whereas inhibition of gamma-glutamyl transpeptidase (acivicin) did not significantly increase the GSH-concentration. Despite these biochemical …
The glutathione content in both epithelial cell lines can be modified by an inhibitor of GSH synthesis (buthionine sulfoximine, BSO), wherea …