新型自然杀伤细胞技术有望彻底阻断癌症

2016-12-16 佚名 生物谷

图片来源:medicalxpress.com 我们的机体中含有自然杀伤细胞(NK细胞),NK细胞能够帮助我们有效阻断癌症和病毒的入侵,最近来自美国中佛罗里达大学医学院的研究人员开发了一种新型的纳米颗粒,在实验室研究中其能够使得NK细胞的数量增加1万倍,目前这项新技术已经获批,未来或有望进行临床试验。 研究者Alicja Copik表示,当我们观察到NK细胞在“撕裂”肿瘤时我们才会意识到机体

图片来源:medicalxpress.com

我们的机体中含有自然杀伤细胞(NK细胞),NK细胞能够帮助我们有效阻断癌症和病毒的入侵,最近来自美国中佛罗里达大学医学院的研究人员开发了一种新型的纳米颗粒,在实验室研究中其能够使得NK细胞的数量增加1万倍,目前这项新技术已经获批,未来或有望进行临床试验。

研究者Alicja Copik表示,当我们观察到NK细胞在“撕裂”肿瘤时我们才会意识到机体的免疫系统是如此强大,这些NK细胞是保护机体的强大军队,其能够有效抵御来自机体外部的异物,比如病原体或肿瘤等。20世纪90年代,当科学家们鉴别并且培养出NK细胞时他们对NK细胞的功能一无所知,从那时候开始,科学家们就大量开发基于NK细胞的疗法来用于多种癌症的治疗;当然此前研究中研究者也试图利用其它类型的细胞(甚至肿瘤细胞)来促进NK细胞生长,但目前困难重重,比如临床试验中其会对患者带来严重的副作用。

这项最新技术利用了纳米颗粒来向NK细胞发送信号使其不断产生,从而抵御癌症,在研究者Copik的实验室中,她们利用来自患者机体中的一个NK细胞,在纳米颗粒的帮助下两周内就能够产生10000个新的NK细胞,这项突破性研究发现解决了目前基于NK细胞疗法开发的瓶颈问题,如果在临床试验中该技术是安全且有效的,那么其或许就能够为很多医院提供新型的细胞疗法,比如进行骨髓抑制为癌症患者提供大量的NK细胞。

这项疗法目前能够有效治疗急性髓性白血病,急性髓性白血病是一种包括骨髓在内的血液形成组织发生的癌症,在后期研究中研究者或将开发出携带信号的纳米颗粒来应对特殊的癌症或病毒,比如HIV和埃博拉病毒等。目前研究者Copik的NK细胞研究获得了两项40万美元的资助,她希望未来能够进行更为深入的研究早日利用安全可靠的新型NK细胞技术来帮助治疗诸如癌症在内等多种疾病。

原始出处

Natural kill cell technology to stop cancer gets licensed

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    2016-12-17 jihuaijun1112

    希望可以成功吧

    0

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    2016-12-16 yafeiliutjh

    拭目以待

    0

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    2016-12-16 thlabcde

    好东西学习了!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1710052, encodeId=3ec01e10052fc, content=<a href='/topic/show?id=7ac59e67604' target=_blank style='color:#2F92EE;'>#阻断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97676, encryptionId=7ac59e67604, topicName=阻断)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b5ca31824852, createdName=41514497@qq.com, createdTime=Tue Oct 10 00:12:00 CST 2017, time=2017-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487928, encodeId=642e148e9286e, content=<a href='/topic/show?id=72a98625851' target=_blank style='color:#2F92EE;'>#自然杀伤细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86258, encryptionId=72a98625851, topicName=自然杀伤细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=43638387861, createdName=habb, createdTime=Sun Dec 18 03:12:00 CST 2016, time=2016-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163602, encodeId=34d4163602f1, content=希望可以成功吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Sat Dec 17 20:14:29 CST 2016, time=2016-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163326, encodeId=3f361633261c, content=拭目以待, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62d381629, createdName=yafeiliutjh, createdTime=Fri Dec 16 19:32:51 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163301, encodeId=3309163301ce, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Fri Dec 16 14:28:29 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163280, encodeId=46b8163280c1, content=只是有望, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Fri Dec 16 13:38:40 CST 2016, time=2016-12-16, status=1, ipAttribution=)]
    2016-12-16 为了宝宝

    只是有望

    0