PLoS One:OCT血管造影术的定量和可重复临床应用研究

2018-07-24 cuiguizhong MedSci原创

法国里昂大学中心住医院眼科的Douma I近日在PLoS One发表了一篇文章,他们针对OCT-A的操作,提出了一种可重复和更加精确的方法,促进临床上定量使用OCT-A。

法国里昂大学中心住医院眼科的Douma I近日在PLoS One发表了一篇文章,他们针对OCT-A的操作,提出了一种可重复和更加精确的方法,促进临床上定量使用OCT-A。

光学相干断层扫描血管造影术(OCT-A)是最近被引入临床的一种眼科成像技术。OCT-A不需要注射造影剂就能够提供三维视网膜血管的可视化图像。因此,OCT-A可以取代目前的眼科成像的标准要求。现在的眼科成像仅是2D的,并且需要造影剂。然而,仍需要进行定量研究以评估OCT-A的全部可能性。

在这种情况下,研究者的这项工作针对OCT-A的操作,提出了一种可重复和更加精确的方法。他们介绍了一种在无血管区域自动提取感兴趣区域的程序,他们在各种无血管区域进行了演示,重点是在特定深度的二维图像中提取的视神经。然后,他们在各种临床设备上使用他们的分割技术,研究OCT-A的可重复性。为了说明,他们将该分割技术应用到健康对照组和不同阶段青光眼(临床感兴趣的疾病)患者身上。与由于仪器或分割算法引起的可变性相比,发现在这两个群组之间观察到的可变性是主要的。

因此,他们认为这项结果促进了临床环境中定量使用OCT-A。

原文出处

Douma, I., et al., Toward quantitative and reproducible clinical use of OCT-Angiography. PLoS One, 2018. 13(7): p. e0197588.

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    2018-07-26 sodoo

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2018CCCP&SCC:李妍教授畅谈OCT对复杂高危患者的指导价值

复杂高危且有介入治疗指征的患者(CHIP)的经皮冠状动脉介入(PCI)治疗一直是介入治疗领域关注的焦点和难点。光学相干断层扫描(OCT)等影像学技术为上述患者的治疗提供了重要指导价值。

Clin Oral Investig:不同浓度的奥替尼啶二盐酸盐漱口水对唾液细菌计数的影响:一项随机、安慰剂对照的交叉试验

这项双中心、安慰剂对照、随机、检测者单盲的不完全临床交叉II阶段试验的目的是为了初期探索奥替尼啶二盐酸盐(OCT)作为口腔清洗剂的最适合浓度。

ESC 2017:韩雅玲院士:我国自主研发的生物可降解支架疗效与安全性好

在ESC科学年会上,韩雅玲院士报告了我国自主研发的新型生物可吸收支架——NeoVas完全可降解支架系统随机对照试验的1年随访结果:NeoVas支架的有效性和安全性不劣于第2代药物洗脱支架Xience,且光学相干断层成像(OCT)结果更佳。

J Periodontal Res:牙周组织形态的光学相干断层扫描观察与测定

诊断是牙周治疗中的关键步骤。本研究的目的是评估光学相干断层扫描(OCT)在体内观察和测定牙周组织形态的有效性。