Neurology:缺血性脑卒中后的头痛发生情况

2020-03-14 MedSci原创 MedSci原创

与缺血性中风相关的头痛知之甚少。本文系统地回顾了研究,以更好的了解新发中风后头痛的患病率和特征。

与缺血性中风相关的头痛知之甚少。本文系统地回顾了研究,以更好的了解新发中风后头痛的患病率和特征。

 

研究人员查询Medline和PubMed数据库,共确定了1,812条文章。其中,有50个被纳入该系统评价。荟萃分析和荟萃分析中包括20个。

 

结果显示,6%-44%缺血性中风人群出现头痛。大多数头痛具有紧张型特征,从中度到重度,并且本质上是慢性的。荟萃分析结果显示,汇总的患病率为0.14(95%置信区间[CI] 0.07-0.23),且各研究之间存在异质性。头痛患病率与研究崎岖,来源人群的国家人类发展指数(HDI)和研究质量之间存在密切关联。我们发现,与中东和亚洲研究地区(0.08,95%CI 0.01-0.18)相比,欧洲(0.22,95%CI 0.14-0.30)和北美研究地区(0.15,95%CI 0.05-0.26)患病率更高。但是,在每个区域中,来自人类发展指数较高的国家(p = 0.03)和具有较高质量的研究(p = 0.001)的人群患病率较低。原始比值比(OR)显示,后循环卒中(合并OR 1.92,95%CI 1.4-2.64;研究n = 7)和女性(合并OR 1.25,95%CI 1.07-1.46;研究n = 11)与缺血性脑卒中相关的头痛的几率更大。

 

综上所述,这些数据表明头痛在缺血性脑卒中发作时或不久后很常见,并且可能导致脑卒中后发病。需要更好地了解与缺血性脑卒中相关的头痛,以建立治疗指南并告知患者管理。

 

原始出处:

 

Andrea M. Harriott, Fahri Karakaya, and Cenk Ayata. Headache after ischemic stroke A systematic review and meta-analysis. Neurology. 2020 Jan 7; 94(1): e75–e86. doi: 10.1212/WNL.0000000000008591

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    2020-04-21 yinhl1978
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    2020-03-14 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0