Stroke:青少年脑卒中患者局灶性脑动脉病

2020-03-26 MedSci原创 MedSci原创

局灶性脑动脉病是一种年轻人动脉缺血性卒中罕见的病因。随访颅内成像检查对鉴别进展性动脉病变至关重要。

局灶性脑动脉病是指颈内动脉远端或大脑中动脉近段的单相型炎性狭窄。它是幼儿急性动脉缺血性卒中最常见的原因之一,但成人神经病学家对它不一定熟悉。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员回顾了2013年1月至2014年12月期间在三级转诊中心的卒中影像学记录。局灶性脑动脉病定义为颈内动脉远端或近端分支的非进行性单侧狭窄/不规则。只有16-55岁的卒中患者被纳入研究。

该研究共纳入5例局灶性脑动脉病患者,2男,3女;其中3例病例来自一个123名急性脑卒中患者的队列,2例来自门诊转诊。患者的平均年龄(范围)为43岁(32-55岁)。大多数患者在数天至数周内因单一血管区域出现反复的短暂性脑缺血发作/轻度卒中。所有病例均有典型的影像学特征。间隔一段时间重复成像检查发现1例患者影像学特征消失,3例显示改善。出院时改良的Rankin评分范围从0到1的患者功能预后良好,1例复发。

由此可见,局灶性脑动脉病是一种年轻人动脉缺血性卒中罕见的病因。随访颅内成像检查对鉴别进展性动脉病变至关重要。

原始出处:

Mary Clare McKenna.et al.Focal Cerebral Arteriopathy in Young Adult Patients With Stroke.stroke.2020.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.028343

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2009694, encodeId=9718200969402, content=<a href='/topic/show?id=c7804e581bc' target=_blank style='color:#2F92EE;'>#局灶性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47581, encryptionId=c7804e581bc, topicName=局灶性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Wed Jun 17 14:46:02 CST 2020, time=2020-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679143, encodeId=94b916e914338, content=<a href='/topic/show?id=7a2684e600b' target=_blank style='color:#2F92EE;'>#脑卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84760, encryptionId=7a2684e600b, topicName=脑卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Oct 25 11:46:02 CST 2020, time=2020-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769228, encodeId=11591e692282a, content=<a href='/topic/show?id=33464e5875e' target=_blank style='color:#2F92EE;'>#局灶性脑动脉病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47587, encryptionId=33464e5875e, topicName=局灶性脑动脉病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e5637990872, createdName=showtest, createdTime=Sat Jun 20 14:46:02 CST 2020, time=2020-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720332, encodeId=cc0c1e20332ed, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Fri Sep 25 20:46:02 CST 2020, time=2020-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026600, encodeId=ab691026600bc, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Fri Mar 27 00:46:02 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2009694, encodeId=9718200969402, content=<a href='/topic/show?id=c7804e581bc' target=_blank style='color:#2F92EE;'>#局灶性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47581, encryptionId=c7804e581bc, topicName=局灶性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Wed Jun 17 14:46:02 CST 2020, time=2020-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679143, encodeId=94b916e914338, content=<a href='/topic/show?id=7a2684e600b' target=_blank style='color:#2F92EE;'>#脑卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84760, encryptionId=7a2684e600b, topicName=脑卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Oct 25 11:46:02 CST 2020, time=2020-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769228, encodeId=11591e692282a, content=<a href='/topic/show?id=33464e5875e' target=_blank style='color:#2F92EE;'>#局灶性脑动脉病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47587, encryptionId=33464e5875e, topicName=局灶性脑动脉病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e5637990872, createdName=showtest, createdTime=Sat Jun 20 14:46:02 CST 2020, time=2020-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720332, encodeId=cc0c1e20332ed, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Fri Sep 25 20:46:02 CST 2020, time=2020-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026600, encodeId=ab691026600bc, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Fri Mar 27 00:46:02 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2009694, encodeId=9718200969402, content=<a href='/topic/show?id=c7804e581bc' target=_blank style='color:#2F92EE;'>#局灶性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47581, encryptionId=c7804e581bc, topicName=局灶性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Wed Jun 17 14:46:02 CST 2020, time=2020-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679143, encodeId=94b916e914338, content=<a href='/topic/show?id=7a2684e600b' target=_blank style='color:#2F92EE;'>#脑卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84760, encryptionId=7a2684e600b, topicName=脑卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Oct 25 11:46:02 CST 2020, time=2020-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769228, encodeId=11591e692282a, content=<a href='/topic/show?id=33464e5875e' target=_blank style='color:#2F92EE;'>#局灶性脑动脉病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47587, encryptionId=33464e5875e, topicName=局灶性脑动脉病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e5637990872, createdName=showtest, createdTime=Sat Jun 20 14:46:02 CST 2020, time=2020-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720332, encodeId=cc0c1e20332ed, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Fri Sep 25 20:46:02 CST 2020, time=2020-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026600, encodeId=ab691026600bc, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Fri Mar 27 00:46:02 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2009694, encodeId=9718200969402, content=<a href='/topic/show?id=c7804e581bc' target=_blank style='color:#2F92EE;'>#局灶性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47581, encryptionId=c7804e581bc, topicName=局灶性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Wed Jun 17 14:46:02 CST 2020, time=2020-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679143, encodeId=94b916e914338, content=<a href='/topic/show?id=7a2684e600b' target=_blank style='color:#2F92EE;'>#脑卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84760, encryptionId=7a2684e600b, topicName=脑卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Oct 25 11:46:02 CST 2020, time=2020-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769228, encodeId=11591e692282a, content=<a href='/topic/show?id=33464e5875e' target=_blank style='color:#2F92EE;'>#局灶性脑动脉病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47587, encryptionId=33464e5875e, topicName=局灶性脑动脉病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e5637990872, createdName=showtest, createdTime=Sat Jun 20 14:46:02 CST 2020, time=2020-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720332, encodeId=cc0c1e20332ed, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Fri Sep 25 20:46:02 CST 2020, time=2020-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026600, encodeId=ab691026600bc, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Fri Mar 27 00:46:02 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2009694, encodeId=9718200969402, content=<a href='/topic/show?id=c7804e581bc' target=_blank style='color:#2F92EE;'>#局灶性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47581, encryptionId=c7804e581bc, topicName=局灶性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Wed Jun 17 14:46:02 CST 2020, time=2020-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679143, encodeId=94b916e914338, content=<a href='/topic/show?id=7a2684e600b' target=_blank style='color:#2F92EE;'>#脑卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84760, encryptionId=7a2684e600b, topicName=脑卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sun Oct 25 11:46:02 CST 2020, time=2020-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769228, encodeId=11591e692282a, content=<a href='/topic/show?id=33464e5875e' target=_blank style='color:#2F92EE;'>#局灶性脑动脉病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47587, encryptionId=33464e5875e, topicName=局灶性脑动脉病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e5637990872, createdName=showtest, createdTime=Sat Jun 20 14:46:02 CST 2020, time=2020-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720332, encodeId=cc0c1e20332ed, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Fri Sep 25 20:46:02 CST 2020, time=2020-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026600, encodeId=ab691026600bc, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Fri Mar 27 00:46:02 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
    2020-03-27 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

相关资讯

Stroke:颈动脉粥样硬化性斑块特点与脑卒中危险指标的相关性

高分辨血管壁磁共振成像能够显示颈动脉斑块形态特点和成分。有许多研究利用2D颈动脉斑块成像技术来评价颈动脉斑块,纵向范围大约为30mm,这对完整显示颅外颈动脉斑块尚不充分。

Stroke:大血管闭塞性脑卒中并ASPECT评分≥6分的患者要不要做介入治疗?

本研究假说在CT上显示急性缺血状态的患者中,发病时软脑膜侧支循环功能能够预测磁共振上脑梗死大小。本研究旨在评价大血管闭塞性脑梗死患者侧支循环功能与扩散加权成像(DWI)上定义的脑梗死体积系列变化间的相关性。

Stroke:用PET评估颈动脉狭窄患者复发性脑卒中的风险!

在症状性颈动脉内膜剥脱术随机试验中,仅有中度狭窄的患者可能从中获益,有些重度狭窄的患者从中并无法获益。颈动脉斑块18F-氟脱氧葡萄糖PET能够反映斑块炎症反应,能够预测复发性脑卒中。

Neurology:静脉溶栓前双抗预治疗的结局

来自美国的 Konark Malhotra 等在 Neurology 上公布了他们的系统性综述和 meta 分析结果,目的在于评价具有 DAPP 病史的急性缺血性卒中患者采取 IVT 的安全性和有效性

Stoke:CT灌注成像在脑卒中合并心功能受损中的应用

左心室射血分数(LVEF)减低会加重脑卒中后预后。本研究旨在验证灌注计算机体层成像中的动脉输入函数(AIF),尤其是扫描开始至AIF结束(SO-EndAIF)时间能够反映心输出量减少。

Stroke:深度学习在脑卒中患者中检出半暗带组织的价值

急性缺血性脑卒中介入治疗患者的选择主要依赖于动态磁敏感对比磁共振成像(DSC-MRI)或计算机体层灌注成像(CTP)。动态磁敏感对比磁共振成像需要注射对比剂才能完成检查,而计算机体层成像灌注又会产生高