重磅!ESC 2017 :《ST段抬高型急性心梗管理指南》发布

2017-08-26 MedSci MedSci原创

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今日,备受瞩目的欧洲心脏病学会(ESC)公布了《ST段抬高型急性心梗(STEMI)管理指南》,该指南是在2012版指南的基础上进行了补充及修订。

该指南首次明确定义了何时开始计时经皮冠状动脉介入治疗(PCI)前的90分钟,应在心电图(ECG)诊断为ST段抬高心肌梗死(STEMI)时开始计时。

此外,新指南删除了“门球时间”这一模糊术语,并将首次医疗接触(FMC)定义为医生、护理人员或护士最初获得并解读ECG的时间。

2012版指南中接受溶栓治疗的病例从STEMI诊断到治疗的最大延迟时间为30分钟,新指南中将这一最大延迟时间改为10分钟。

2012版指南不推荐完全血运重建,推荐只对梗死相关动脉进行治疗。新指南推荐考虑完全血运重建,评估时或出院前择期对非梗死相关动脉进行治疗。

基于纳入15000多名受试者的两项大型试验的研究结果,新指南不再推荐血栓抽吸。同时也不推荐推迟介入,包括疏通动脉并等待48小时再植入支架。至于PCI,新指南更强调了使用药物涂层支架而非裸金属支架,使用桡动脉入路而非股动脉入路。

在药物治疗方面,指南推荐对于选定的患者双联抗血小板治疗可超过12个月。新指南中使用比伐卢定的等级由I变为了IIa,依诺肝素则由IIb变为IIa。2012版指南中并未提及坎格瑞洛,而新指南中推荐部分选定的患者可使用此药。此外,新指南指出,高胆固醇患者经最大剂量他汀治疗后效果仍不理想者可额外使用其他降脂药物。

新指南将氧疗的临界值由原来的动脉血氧饱和度95%给予氧疗降为90%。当患者出现缺血症状时,左及右束支阻滞被认为是行紧急血管造影的依据。

新指南华介绍了非阻塞性冠脉疾病(MINOCA),约占STEMI患者的14%,需要额外的诊断测试以及可能不同于典型STEMI患者的个体化治疗。

此外,新指南中写入了大量的诊疗流程图和简洁的推荐,将有助于临床医生快速诊断和治疗STEMI患者。

原始出处:

ESC Guidelines on ST-segment elevation myocardial infarction published today. 26 Aug 2017.

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    2017-08-28 gdsun
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    2017-08-28 xxxx1054
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    2017-08-28 hyf035
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    2017-08-28 戒馋,懒,贪

    谢谢分享

    0

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    2017-08-28 inter158

    新指南指出.高胆固醇患者经最大剂量他汀治疗后效果仍不理想者可额外使用其他降脂药物.

    0