JAHA:心肌内出血会影响STEMI患者预后

2017-08-16 MedSci MedSci原创

微血管损伤包括微血管的破坏和心肌内出血(IMH),既往研究显示ST段抬高型梗死(STEMI)患者伴有心肌内出血的预后要比没有出血的差,但是预测STEMI后的IMH研究尚缺乏。近日,在国际心血管权威杂志JAHA上发表了一篇旨在评估STEMI患者中IMH的流行病学资料和分析其对临床预后影响的临床研究。本研究纳入的研究对象是经皮冠脉介入治疗后5.5±1.8天行心脏磁共振检查的STEMI患者,微血管梗阻和

微血管损伤包括微血管的破坏和心肌内出血(IMH),既往研究显示ST段抬高型梗死(STEMI)患者伴有心肌内出血的预后要比没有出血的差,但是预测STEMI后的IMH研究尚缺乏。近日,在国际心血管权威杂志JAHA上发表了一篇旨在评估STEMI患者中IMH的流行病学资料和分析其对临床预后影响的临床研究。本研究纳入的研究对象是经皮冠脉介入治疗后5.5±1.8天行心脏磁共振检查的STEMI患者,微血管梗阻和心肌内出血分别由延迟钆增强和T2加权心血管磁共振成像诊断。最终共纳入410名患者,其中54%伴有心肌内出血。研究结果显示IMH与心肌前壁梗塞(OR, 2.96; 95% CI, 1.73-5.06 [P<0.001])和围手术期糖蛋白IIb/IIIa抑制剂治疗(OR, 2.67; 95% CI, 1.49-4.80 [P<0.001])呈相关性。IMH及其程度与梗塞面积的扩大、微血管阻塞、较大尺寸的左心室和较低的左心室射血分数呈相关性(P<0.001)。研究结果显示,心肌内出血与STEMI患者的前壁梗塞和围手术期糖蛋白IIb/IIIa抑制剂治疗呈相关性,影响患者预后。原始出处

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    2017-08-18 zhaohui6731
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    2017-08-18 yfjms

    学习了

    0

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    2017-08-17 ylzr123

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

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    2017-08-16 changjiu

    学习了,谢谢

    0

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