Emerg Infect Dis:1983-2015韩国感染性疾病死亡率趋势分析研究

2018-02-05 SIFIC循证 SIFIC感染官微

感染性疾病/传染性疾病的发生率、死亡率往往与社会的经济、卫生水平相关。过去的20年,随着全球经济贸易一体化,韩国的经济也呈快速发展趋势,常见的感染性疾病/传染性疾病的发病率、死亡率总体降低,但是随着新发、突发传染病的出现(例如2009年的H1N1流感、2015年的中东呼吸综合征),老龄化的趋势,韩国感染性疾病/传染性疾病的防控工作迎来了新的挑战。

编者按

感染性疾病/传染性疾病的发生率、死亡率往往与社会的经济、卫生水平相关。过去的20年,随着全球经济贸易一体化,韩国的经济也呈快速发展趋势,常见的感染性疾病/传染性疾病的发病率、死亡率总体降低,但是随着新发、突发传染病的出现(例如2009年的H1N1流感、2015年的中东呼吸综合征),老龄化的趋势,韩国感染性疾病/传染性疾病的防控工作迎来了新的挑战。这篇文献分析了韩国20年来感染性/传染性疾病的特点及趋势,为下一步防控重点提供了数据支持。

使用1983-2015全国统计数据评估因感染性疾病死亡的趋势。年龄标准化的感染性疾病死亡率从1983年43.5/10万人口降低到1996年16.5/10万人口,2015年增加到44.6/10万人口。1993年最常见的致死原因是肺结核,而2015年最常见的是呼吸道感染。我们观察到感染性疾病导致的婴儿死亡显着下降。但65岁及以上人群的死亡率从1996年的135/10万人口增加到2015年的307/10万人口。呼吸道感染、脓毒血症和肺结核的标化感染率呈现增加的趋势。尽管在婴儿死亡率上取得实质性进展,但总体来说感染性疾病死亡率并未降低。低文化程度的老年人群、易患呼吸道感染和脓毒血症的人群是韩国感染性疾病/传染性疾病预防控制政策方面的重点。

我们从韩国统计信息服务(KOSIS,http://kosis.kr/eng)数据库回顾1983-2015年感染性疾病死亡率并列出感染性疾病组别(见表1)

表1 选出的感染性疾病组别及对应的ICD-10编码*



结果:

从1983到2015年,感染性疾病死亡数呈现U形趋势,但非感染性疾病死亡数从每10万人口594.3下降至496.9。(见图1)。


图1 感染性疾病、非感染性疾病、以及全部疾病的年龄标准化死亡率(死亡人数/10万人口)

1993年最常见的致死原因是肺结核(死亡7853; 23.7/10万人口) ,而2015年最常见的是呼吸道感染 (死亡15030; 19.5/10万人口)。(见表2)

表2 感染性疾病主要死亡病因,韩国,1983-2015



我们根据年龄组分析了死亡率(见图2)。感染性疾病导致的婴儿(<1岁)死亡有了显着下降。但65岁及以上的人群死亡率从1996年的135/10万人口增加到2015年的307/10万人口。


图2 不同年龄组感染性疾病死亡率(死亡人数/10万人口)

使用衔接点分析法分析了不同年龄组感染性疾病死亡率的趋势。

表3 不同年龄组感染性疾病相关死亡率趋势,使用链接点分析法,韩国,1983-2015*



我们分析了呼吸道感染、脓毒血症和肺结核的年龄标准化死亡率,以及肠道感染、疫苗可预防的疾病、中枢神经系统感染和病毒性肝炎的死亡率(图3)


图3 年龄标准化感染性疾病死亡率,韩国,1983-2015.A)呼吸道感染、脓毒血症和肺结核相关的死亡率B)肠道感染、疫苗可预防的疾病、中枢神经系统感染和病毒性肝炎的死亡率

感染性疾病的死亡率变化多样。肺结核、脓毒血症和病毒性肝炎的死亡率从1983到2015年呈现出的变化波动最大。见表4。

表4 感染性疾病相关年龄标准化死亡率趋势,使用链接点分析法,韩国,1983-2015*



我们根据文化程度分层统计了65岁以上人群的感染性疾病死亡率(表5)

低文化程度的老年人群及亚组易患呼吸道感染和脓毒血症的人群是预防政策方面的重点。

表5 65岁以上人群呼吸道感染、脓毒血症和肺结核的年龄标准化死亡率的变化根据文化程度和不平等指数,韩国,2000-2015



原始出处:Choe YJ, Choe SA, Cho SI. Trends in Infectious Disease Mortality, South Korea,1983-2015. Emerg Infect Dis. 2018, 24(2):320-327.

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level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Mon Feb 05 08:49:47 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285301, encodeId=d779285301cf, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Feb 05 08:33:12 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285295, encodeId=eede28529509, content=学习谢谢分享, 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    2018-02-19 大爰

    学习了谢谢分享!!

    0

  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Mon Feb 05 08:26:38 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-02-07 大爰

    学习了谢谢分享!!

    0

  7. 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  8. 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level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Mon Feb 05 08:49:47 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285301, encodeId=d779285301cf, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Feb 05 08:33:12 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285295, encodeId=eede28529509, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Mon Feb 05 08:26:38 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-02-05 大爰

    学习并分享!!

    0

  9. 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level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Mon Feb 05 08:49:47 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285301, encodeId=d779285301cf, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Feb 05 08:33:12 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285295, encodeId=eede28529509, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Mon Feb 05 08:26:38 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-02-05 明月清辉

    谢谢分享.学习了

    0

  10. 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    2018-02-05 龙胆草

    学习谢谢分享

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