Circulation:疤痕相关室性心动过速(VT)改良新终点

2012-04-11 贾丽芳译 医学论坛网

  研究显示,对于疤痕相关的室性心动过速(VT),明确局部异常心室活动(LAVA)并消除LAVA 是安全可行的,患者存活率更高,且可避免VT复发。该研究2012年4月4日在线发表于《循环》(Circulation)杂志。   导管消融治疗VT有效,而且在需要经常除颤的患者中特别有用,对于不能描记的或血流动力学不耐受的VT,有各种不同的基质改良技术。非诱导性是最常被使用的VT终点,但其有

  研究显示,对于疤痕相关的室性心动过速(VT),明确局部异常心室活动(LAVA)并消除LAVA 是安全可行的,患者存活率更高,且可避免VT复发。该研究2012年4月4日在线发表于《循环》(Circulation)杂志。

  导管消融治疗VT有效,而且在需要经常除颤的患者中特别有用,对于不能描记的或血流动力学不耐受的VT,有各种不同的基质改良技术。非诱导性是最常被使用的VT终点,但其有明显局限性如最佳治疗终点仍不明确。该研究假设在窦性心律或人工心室起搏时消除LAVA有效。

  研究共入组心室结构异常的VT患者70例,67例记录到LAVA,将冲洗尖端导管通过跨室间隔或者降主动脉置于心内膜,或者经剑突下置于心外膜,进行LAVA导管消融。其中47例成功进行了导管消融,LAVA被消除或分离。在平均22个月的长期随访中,LAVA消除与VT复发或死亡减少独立相关。

  链接:

  Elimination of Local Abnormal Ventricular Activities: A New End Point for Substrate Modification in Patients with Scar-Related Ventricular Tachycardia

  



    

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